According to BioCrossroads, Indiana’s life sciences sector alone accounts for over $80 billion in economic output annually—ranking among the top five U.S. states in life sciences exports. Additionally, the Indianapolis metro area is home to more than 2,100 tech companies, according to TechPoint, the state’s nonprofit growth accelerator for tech.
From Eli Lilly’s global headquarters to a surge in biotech startups and health-tech accelerators, the city is cultivating the perfect ecosystem for office labs, R&D flex space, and innovation-driven facilities. With Indiana’s business-friendly tax environment and competitive cost of living, entrepreneurs and Fortune 500 companies alike are seeing Indy as fertile ground for long-term CRE investments.

The Rise of Flex and Hybrid Workspaces
The hybrid work model is reshaping commercial space needs. Startups and midsize companies are increasingly seeking flexible tech office space in Indianapolis—blending traditional layouts with collaborative zones, smart infrastructure, and built-in connectivity for rapid scaling.
On the life sciences front, demand is shifting toward wet and dry lab combinations, proximity to academic institutions (like Indiana University and Purdue), and access to high-quality utilities and transportation corridors. Submarkets like Carmel, Fishers, and Downtown Indy are seeing a particular spike in interest.
Investment Opportunity: CRE for Emerging Industries
As a licensed commercial real estate broker in Indiana, I work closely with clients looking to buy, sell, or lease within these evolving sectors. Whether it’s acquiring R&D flex space for biotech ventures, securing prime locations for a scaling tech firm, or repositioning outdated buildings into high-performance workspaces, the key is understanding the pulse of the industries shaping Indiana’s future.
With data showing Indianapolis office vacancy rates hovering near 17% (Q1 2024, Colliers), it’s a tenant-friendly market with significant upside for the right investments—especially in adaptive reuse and new development tailored to science and tech.
Why Now is the Right Time
2025 is primed for growth. The state has launched multiple funding initiatives to support innovation and advanced industries, including the Indiana Economic Development Corporation’s $500M READI program aimed at regional economic acceleration.
For CRE buyers, that means access to grants, zoning support, and infrastructure investment that can unlock long-term value. For tenants, it means smarter buildings, better locations, and more negotiation power.
Looking for Tech or Life Sciences Real Estate in Indianapolis?
Whether you’re a startup founder needing a high-tech hub or a biotech executive expanding R&D operations, I’m here to help you navigate the local CRE landscape. With deep knowledge of the Indianapolis commercial market, and a pulse on the state’s tech and life sciences trends, I’ll help you secure the right property to scale your business—and maximize your return.
Let’s talk strategy, space, and success.
Reach out today to schedule a discovery call and explore your CRE options.
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